Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 9/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 5/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30174197 | 0.77 | P2RX3 (0.40) | P2RX3MEN1KMT2AHCAR2 | |
| SCHEMBL25529033 | 0.77 | P2RX3 (0.40) | P2RX3MEN1KMT2AHCAR2 | |
| SCHEMBL72281 | 0.76 | PDE10A (0.45) | MEN1KMT2AADORA3PDE10AKDM4E | |
| SCHEMBL4173266 | 0.72 | KMT2A (0.54) | MEN1KMT2AADORA3PDE10AKDM4E | |
| SCHEMBL25210352 | 0.71 | MAPK1 (0.45) | P2RX3MEN1KMT2AHCAR2KDM4E | |
| SCHEMBL30063260 | 0.71 | MAPK1 (0.45) | P2RX3MEN1KMT2AHCAR2KDM4E | |
| SCHEMBL6730304 | 0.70 | PTPN1 (0.37) | P2RX3ADORA3HCAR2DPP4DPP8 | |
| SCHEMBL2130302 | 0.70 | ALDH1A1 (0.51) | MEN1KMT2AHCAR2KDM4E | |
| SCHEMBL30843807 | 0.69 | ALDH1A1 (0.35) | P2RX3MEN1KMT2AHCAR2PDE10A | |
| SCHEMBL27918574 | 0.69 | KDM4E (0.35) | MEN1KMT2AKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336774-A | 1,4-dihydropyridine 3,5 carboxyl compounds | ACHIWA KAZUO (JP) | 1994-08-09 | — | — | US | disclosed |