Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16806284 | 0.90 | PDE10A (0.47) | PDE10AALDH1A1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL4173266 | 0.85 | KMT2A (0.54) | PDE10AALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8874663 | 0.84 | PDE10A (0.52) | PDE10AALDH1A1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL31633610 | 0.84 | PDE10A (0.52) | PDE10AALDH1A1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL26967850 | 0.81 | P2RX3 (0.41) | PDE10AALDH1A1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL29798822 | 0.80 | KMT2A (0.46) | PDE10AALDH1A1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL15316166 | 0.80 | PDE10A (0.44) | PDE10AALDH1A1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL207579 | 0.78 | NOTUM (0.42) | PDE10AALDH1A1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL829193 | 0.78 | NOTUM (0.42) | PDE10AALDH1A1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL5514920 | 0.78 | ALDH1A1 (0.41) | PDE10AALDH1A1SMN1; SMN2MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1085200-C | Process for producing dimethylamine | MITSUBISHI NITTO K K (JP) | 2002-05-22 | — | — | CN | claimed |
| CN-115322995-B | Action of DNA methyltransferase Dnmt2 in liver injury repair | 华中农业大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-115322995-A | Role of DNA methyltransferase Dnmt2 in liver injury repair | 华中农业大学 | 2022-11-11 | — | — | CN | disclosed |
| US-8445533-B2 | Andrographolide derivatives to treat viral infections | CORNELL RESEARCH FOUNDATION, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| EP-2479203-A1 | AROMATIC POLYESTER | Muroran Institute of Technology (JP) | 2012-07-25 | — | — | EP | disclosed |
| US-20120172570-A1 | AROMATIC POLYESTER | NITTA CORPORATION | 2012-07-05 | — | — | US | disclosed |
| US-8129493-B2 | Aromatic polyester | MURORAN INSTITUTE OF TECHNOLOGY (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20110224343-A1 | MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME | MURORAN INSTITUTE OF TECHNOLOGY (JP) | 2011-09-15 | — | — | US | disclosed |
| US-20110092662-A1 | AROMATIC POLYESTER | NITTA CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
| EP-1817024-A2 | ANDROGRAPHOLIDE DERIVATIVES TO TREAT VIRAL INFECTIONS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2007-08-15 | — | — | EP | disclosed |
| US-20060223785-A1 | Andrographolide derivatives to treat viral infections | CORNELL RESEARCH FOUNDATION, INC. | 2006-10-05 | — | — | US | disclosed |
| WO-2006101538-A2 | ANDROGRAPHOLIDE DERIVATIVES TO TREAT VIRAL INFECTIONS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224343-A1 | MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME | F12, PHAX, WDR82 | PDE10A 2818/4885ALDH1A1 1882/4885SMN1; SMN2 4357/4885 |
| US-20060223785-A1 | Andrographolide derivatives to treat viral infections | HAVCR2, MAVS, EIF2AK2 | PDE10A 2673/4885ALDH1A1 897/4885SMN1; SMN2 3651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.