Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A2 | O94788 | 2/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL7169891 | 0.92 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL1645736 | 0.84 | NPC1 (0.62) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL3894978 | 0.84 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL873426 | 0.84 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL1853028 | 0.84 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL3885389 | 0.84 | MAPT (0.57) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL1849445 | 0.84 | RAB9A (0.62) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL29089761 | 0.84 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL28658650 | 0.84 | NPC1 (0.62) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL3895951 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304638-A | Anti-aging high-temperature-resistant plastic for automotive interior parts and preparation method thereof | 上海瀚氏科技集团有限公司 | 2023-12-29 | — | — | CN | claimed |
| CN-111269228-B | Preparation method of indolizine ring-1, 2-diketone and derivative thereof with fluorescence activity | 广东药科大学 | 2021-04-23 | — | — | CN | claimed |
| CN-111269228-A | Preparation method of indolizine ring-1, 2-diketone and derivative thereof with fluorescence activity | 广东药科大学 | 2020-06-12 | — | — | CN | claimed |
| CN-111138432-A | Method for preparing pyrrole [2,1,5-cd ] indolizine ring derivative through metal-free photocatalysis | 广东药科大学 | 2020-05-12 | — | — | CN | claimed |
| CN-110498797-A | Pyrrolo- [2,1,5-cd] indolizine cyclics and its synthetic method | UNIV GUANGDONG PHARM | 2019-11-26 | — | — | CN | claimed |
| US-6572664-B2 | Oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2003-06-03 | — | — | US | claimed |
| US-20020170121-A9 | Indolizine derivatives, compositions comprising at least one coupler chosen from indolizine derivatives and at least one oxidation base, and methods for using same | L'OREAL S.A. (FR) | 2002-11-21 | — | — | US | claimed |
| US-20020002749-A1 | Indolizine derivatives, compositions comprising at least one coupler chosen from indolizine derivatives and at least one oxidation base, and methods for using same | BRETON PHILIPPE (FR) | 2002-01-10 | — | — | US | claimed |
| EP-1129691-A2 | Compositions for dyeing keratinous fibers containing indolizine derivatives and dyeing method using same | L'OREAL (FR) | 2001-09-05 | — | — | EP | claimed |
| CN-117758282-B | Electrocatalytic preparation method of (indolizine-3-yl) -ethanedione derivative | 上海陶术生物科技有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-115537853-B | Direct electrochemical synthesis method of triarylamine compound | 浙江工业大学 | 2025-01-10 | — | — | CN | disclosed |
| CN-117758282-A | Electrocatalytic preparation method of (indolizine-3-yl) -ethanedione derivative | 上海陶术生物科技有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117304638-A | Anti-aging high-temperature-resistant plastic for automotive interior parts and preparation method thereof | 上海瀚氏科技集团有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-117304638-A | Anti-aging high-temperature-resistant plastic for automotive interior parts and preparation method thereof | 上海瀚氏科技集团有限公司 | 2023-12-29 | — | — | CN | disclosed |
| US-4334072-A | CHROMOGENS, LEUCO DYES | APPLETON PAPERS INC. (US) | 1982-06-08 | — | — | US | disclosed |
| EP-0043858-A1 | HETERO RING-SUBSTITUTED OXOALKANOIC ACID DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1982-01-20 | — | — | EP | disclosed |
| US-4275206-A | CHROMOGENS FOR RECORDING AND MARKING SYSTEMS | APPLETON PAPERS INC. (US) | 1981-06-23 | — | — | US | disclosed |
| EP-0026859-A2 | Image-forming photosensitive composition, photosensitive coating solution and photosensitive sheet comprising this composition | ORIENTAL PHOTO INDUSTRIES, CO., LTD. (JP) | 1981-04-15 | — | — | EP | disclosed |
| US-4232887-A | PRESSURE SENSITIVE AND HEAT SENSITIVE ELEMENTS FOR RECORDING | APPLETON PAPERS INC. (US) | 1980-11-11 | — | — | US | disclosed |
| US-4103012-A | CARDIOVASCULAR DISORDERS | LABAZ (FR) | 1978-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020002749-A1 | Indolizine derivatives, compositions comprising at least one coupler chosen from indolizine derivatives and at least one oxidation base, and methods for using same | KRT18, INMT, IDO1 | ALDH1A1 897/4885MAPT 181/4885KDM4E 1225/4885 |
| US-20020170121-A9 | Indolizine derivatives, compositions comprising at least one coupler chosen from indolizine derivatives and at least one oxidation base, and methods for using same | KRT18, INMT, IDO1 | ALDH1A1 897/4885MAPT 181/4885KDM4E 1225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.