SCHEMBL9427744 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	MMP2	P08253	1/20	0.35

▸	ANPEP	P15144	1/20	0.35

▸	GBA2	Q9HCG7	1/20	0.34

▸	LMNA	P02545	1/20	0.32

▸	POLB	P06746	1/20	0.32

▸	SMN1; SMN2	Q16637	1/20	0.32

▸	HPGD	P15428	1/20	0.30

▸	ATM	Q13315	1/20	0.30

▸	L3MBTL1	Q9Y468	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9635513	0.91	GBA2 (0.37)	MMP2ANPEPGBA2LMNAPOLB
SCHEMBL9595859	0.86	MMP2 (0.45)	MMP2ANPEPGBA2LMNAPOLB
SCHEMBL14951725	0.86	MMP2 (0.45)	MMP2ANPEPGBA2LMNAPOLB
SCHEMBL9595866	0.86	MMP2 (0.45)	MMP2ANPEPGBA2LMNAPOLB
SCHEMBL7809194	0.83	MMP2 (0.35)	MMP2ANPEPPOLB
SCHEMBL21702575	0.80	MMP2 (0.49)	MMP2ANPEPLMNAL3MBTL1
SCHEMBL4367951	0.74	MMP2 (0.40)	MMP2ANPEPLMNAATM
SCHEMBL9635638	0.74	GBA2 (0.44)	MMP2GBA2LMNAPOLBSMN1; SMN2
SCHEMBL9635642	0.74	GBA2 (0.44)	MMP2GBA2LMNAPOLBSMN1; SMN2
SCHEMBL9732258	0.74	MMP2 (0.37)	MMP2ANPEPLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5317016-A	Pyrrolidylthiocarbapenem derivative	SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP)	1994-05-31	—	—	US	disclosed