Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5173197 | 0.78 | SMN1; SMN2 (0.45) | MAOAMAOBSMN1; SMN2MAPTHPGD | |
| SCHEMBL343269 | 0.78 | SMN1; SMN2 (0.45) | MAOAMAOBSMN1; SMN2MAPTHPGD | |
| SCHEMBL1453001 | 0.78 | SMN1; SMN2 (0.45) | MAOAMAOBSMN1; SMN2MAPTHPGD | |
| SCHEMBL1713865 | 0.77 | SMN1; SMN2 (0.50) | MAOAMAOBSMN1; SMN2MAPTHPGD | |
| Fluoride SCHEMBL1336886 | 0.76 | MAOA (0.48) | MAOAMAOBSMN1; SMN2MAPTHPGD | |
| SCHEMBL23331965 | 0.74 | MAOA (0.52) | MAOAMAOBSMN1; SMN2MAPTHPGD | |
| SCHEMBL7362590 | 0.74 | MAOA (0.52) | MAOAMAOBSMN1; SMN2MAPTHPGD | |
| SCHEMBL3885342 | 0.74 | MAOA (0.41) | MAOAMAOBSMN1; SMN2MAPTHPGD | |
| SCHEMBL24012949 | 0.74 | MAOA (0.41) | MAOAMAOBSMN1; SMN2MAPTHPGD | |
| SCHEMBL95522 | 0.74 | LMNA (0.42) | MAOAMAOBSMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283341-A | Catalytic alkylation | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1994-02-01 | — | — | US | disclosed |
| EP-0516982-A1 | Process for producing a heterocyclic tertiary amine | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-12-09 | — | — | EP | disclosed |