Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427855 | 1.00 | CACNA1C (0.36) | CACNA1CESR1PTGS1PDE4AFAP | |
| SCHEMBL8046007 | 0.88 | CACNA1C (0.36) | CACNA1CESR1PTGS1PDE4AFAP | |
| SCHEMBL9834843 | 0.86 | ESR1 (0.37) | CACNA1CESR1PTGS1PDE4AFAP | |
| SCHEMBL8038860 | 0.86 | ESR1 (0.37) | CACNA1CESR1PTGS1PDE4AFAP | |
| SCHEMBL9698199 | 0.85 | ELANE (0.31) | CACNA1C | |
| SCHEMBL9428111 | 0.83 | ELANE (0.36) | CACNA1CESR1PTGS1PDE4A | |
| SCHEMBL8839225 | 0.82 | ELANE (0.31) | CACNA1C | |
| SCHEMBL30006016 | 0.82 | ELANE (0.31) | CACNA1C | |
| SCHEMBL9427926 | 0.81 | — | — | |
| SCHEMBL8975911 | 0.78 | MAPT (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5306816-A | Processes for preparing carbapenem derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0499196-A1 | Intermediates and process for preparing carbapenem derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-19 | — | — | EP | disclosed |