SCHEMBL9428239

SCHEMBL9428239

Sc1ccc2nnsc2c1S

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.32
MLLT1 Q03111 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9428376 0.68
SCHEMBL9428120 0.65
SCHEMBL9428497 0.64 THRB (0.37) THRBMLLT1
SCHEMBL3701133 0.63 NOTUM (0.33)
SCHEMBL19738041 0.60 ERN1 (0.45) THRB
SCHEMBL331705 0.59
SCHEMBL29364936 0.59
SCHEMBL9666635 0.59 BAZ1A (0.33)
SCHEMBL21718809 0.57 CA2 (0.39)
SCHEMBL29281194 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4908144-A Reaction product of dimercaptothiadiazole with an epoxide to form an alcohol, which is reacted with hydrocarbyl succinic anhydride to form an ester which is reacted with an amine MOBIL OIL CORPORATION (US) 1990-03-13 US claimed
US-5336420-A Reaction product of mercaptoheterocyclic compounds with quaternary ammonium salts and hydrocarbon-substituted succinic anhydride MOBIL OIL CORPORATION (US) 1994-08-09 US disclosed
US-5217502-A Fuel, oil additives MOBIL OIL CORPORATION (US) 1993-06-08 US disclosed
US-5194167-A For lubricatns and fuels MOBIL OIL CORPORATION (US) 1993-03-16 US disclosed
US-5137649-A Lubricants MOBIL OIL CORPORATION (US) 1992-08-11 US disclosed
US-5126397-A Oil additives MOBIL OIL CORPORATION (US) 1992-06-30 US disclosed
EP-0284676-B1 MERCAPTO-THIADIAZOLE REACTION PRODUCTS AS MULTIFUNCTIONAL LUBRICANT ADDITIVES AND COMPOSITIONS THEREOF MOBIL OIL CORPORATION (US) 1991-12-04 EP disclosed
US-5006271-A Organosulfur adducts as multifunctional additives for lubricating oils and fuels and as multifunctional lubricants MOBIL OIL CORPORATION (US) 1991-04-09 US disclosed
US-4908144-A Reaction product of dimercaptothiadiazole with an epoxide to form an alcohol, which is reacted with hydrocarbyl succinic anhydride to form an ester which is reacted with an amine MOBIL OIL CORPORATION (US) 1990-03-13 US disclosed
US-4906393-A Mixed phenol/dimercaptothiadiazole-derived hydroxythioether borates as antioxidant/antiwear multifunctional additives MOBIL OIL CORPORATION (US) 1990-03-06 US disclosed
EP-0284676-A1 Mercapto-thiadiazole reaction products as multifunctional lubricant additives and compositions thereof MOBIL OIL CORPORATION (US) 1988-10-05 EP disclosed
US-4661273-A WEAR RESISTANCE, OXIDATIN RESISTANCE MOBIL OIL COMPANY (US) 1987-04-28 US disclosed