SCHEMBL9428283

SCHEMBL9428283

CCS(=O)(=O)Nc1ccc(F)c(-n2nc(C)n(C(F)F)c2=O)c1

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPOX P50336 1/20 0.49
AR P10275 2/20 0.40
BRD4 O60885 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9428146 0.81 PPOX (0.45) PPOXARBRD4
SCHEMBL20267538 0.78 PPOX (0.47) PPOX
SCHEMBL30537050 0.78 PPOX (0.47) PPOX
SCHEMBL29574794 0.77 PPOX (0.72) PPOX
SCHEMBL7048169 0.76 BRPF1 (0.42) ARBRD4
Propionic Acid SCHEMBL27682308 0.74 PPOX (0.45) PPOX
SCHEMBL9428190 0.73 PPOX (0.43) PPOX
SCHEMBL6659733 0.73 PPOX (0.46) PPOX
SCHEMBL27657198 0.72 PPOX (0.45) PPOX
SCHEMBL6658377 0.71 PPOX (0.51) PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5294595-A 2-(2-Halo-5-sulfoamido-phenyl),5-oxo-1,2,4-triazoles and an additional herbicide with a carrier FMC CORPORATION (US) 1994-03-15 US disclosed
EP-0294375-B1 HERBICIDAL ARYL TRIAZOLINONES FMC Corporation (US) 1993-08-18 EP disclosed
US-5174809-A Herbicidal aryl triazolinones FMC CORPORATION (US) 1992-12-29 US disclosed
US-5041155-A Preemergence herbicide mixture for controlling grass; for use with soybeans, corn or sugar cane FMC CORPORATION (US) 1991-08-20 US disclosed
US-4818275-A PREEMERGENCE FMC CORPORATION (US) 1989-04-04 US disclosed
EP-0294375-A1 HERBICIDAL ARYL TRIAZOLINONES. FMC CORP (US) 1988-12-14 EP disclosed
EP-0294375-A4 HERBICIDAL ARYL TRIAZOLINONES. FMC CORP (US) 1988-10-20 EP disclosed
WO-1987003782-A1 HERBICIDAL ARYL TRIAZOLINONES FMC CORPORATION (US) 1987-07-02 WO disclosed