SCHEMBL7048169

SCHEMBL7048169

CCS(=O)(=O)Nc1ccc(F)c(-n2nc(C(F)(F)F)n(C)c2=O)c1

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BRPF1 P55201 1/20 0.42
PGR P06401 3/20 0.41
KIF11 P52732 1/20 0.40
DHODH Q02127 5/20 0.40
AR P10275 4/20 0.39
BRD4 O60885 7/20 0.38
NR3C1 P04150 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6308458 0.78 PGR (0.40) PGRDHODHARBRD4
Potassium SCHEMBL7157685 0.77 PGR (0.39) PGRDHODHARBRD4
SCHEMBL7157679 0.77 PGR (0.39) PGRDHODHARBRD4
SCHEMBL7021154 0.76 BRPF1 (0.44) BRPF1PGRKIF11ARBRD4
SCHEMBL9428283 0.76 PPOX (0.49) ARBRD4
SCHEMBL28999713 0.76 DHODH (0.38) PGRDHODH
SCHEMBL39236 0.76 DHODH (0.43) DHODH
SCHEMBL8517457 0.75 DHODH (0.47) DHODH
SCHEMBL9730340 0.73 BRPF1 (0.38) BRPF1PGRARBRD4NR3C1
Chlorthiamid SCHEMBL5268335 0.71 DHODH (0.42) DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1429612-A1 HERBICIDES CONTAINING SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONE Bayer CropScience AG (DE) 2004-06-23 EP disclosed
WO-2003026426-A1 HERBICIDES CONTAINING SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONE BAYER CROPSCIENCE AG (DE) 2003-04-03 WO disclosed