SCHEMBL9429055

SCHEMBL9429055

C=CCOC(=O)C(N1C(=O)[C@H]([C@@H](C)O[Si](C)(C)C(C)(C)C)[C@H]1CC(=S)SC)=P(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FAAH O00519 8/20 0.34
ELANE P08246 1/20 0.32
MGLL Q99685 1/20 0.32
CASP1 P29466 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7636396 0.91 CASP1 (0.33) FAAHELANEMGLLCASP1
SCHEMBL9428362 0.87 FAAH (0.32) FAAHELANEMGLL
SCHEMBL7629806 0.87 PKM (0.32) FAAHELANEMGLL
SCHEMBL13946840 0.86 ELANE (0.34) FAAHELANE
SCHEMBL14517824 0.86 ELANE (0.34) FAAHELANE
SCHEMBL14517846 0.86 ELANE (0.32) FAAHELANE
SCHEMBL13946832 0.85 ELANE (0.34) FAAHELANEMGLL
SCHEMBL14517839 0.85 IDO1 (0.38) FAAHELANE
SCHEMBL5427057 0.84 ELANE (0.33) FAAHELANEMGLLCASP1
SCHEMBL14517849 0.84 ELANE (0.32) FAAHELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5306816-A Processes for preparing carbapenem derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-04-26 US disclosed
EP-0499196-A1 Intermediates and process for preparing carbapenem derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-08-19 EP disclosed