Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 10/20 | 0.69 |
| ▸ | RXRA | P19793 | 4/20 | 0.62 |
| ▸ | RXRB | P28702 | 4/20 | 0.62 |
| ▸ | RXRG | P48443 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7503287 | 0.88 | PTGS2 (0.63) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL7504853 | 0.88 | PTGS2 (0.63) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL7504069 | 0.87 | NR4A2 (0.53) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL7510938 | 0.87 | NR4A2 (0.53) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL2117681 | 0.84 | NR4A2 (0.63) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL14289415 | 0.82 | NR4A2 (0.75) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL5098755 | 0.82 | NR4A2 (1.00) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL10029680 | 0.82 | NR4A2 (0.80) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL8556511 | 0.81 | NR4A2 (0.46) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL8560591 | 0.81 | NR4A2 (0.46) | NR4A2RXRARXRBRXRGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348969-A | Oxazole derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-09-20 | — | — | US | claimed |
| WO-2024009283-A1 | AT2 ANTAGONISTS FOR NON-ADDICTIVE PAIN RELIEF | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2024-01-11 | — | — | WO | disclosed |
| US-5348969-A | Oxazole derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-09-20 | — | — | US | disclosed |