Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 7/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | RXRA | P19793 | 2/20 | 0.58 |
| ▸ | RXRB | P28702 | 2/20 | 0.58 |
| ▸ | RXRG | P48443 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7500361 | 0.89 | PTGS2 (0.62) | NR4A2KMT2ARXRARXRBRXRG | |
| SCHEMBL7501340 | 0.89 | PTGS2 (0.62) | NR4A2KMT2ARXRARXRBRXRG | |
| SCHEMBL7499057 | 0.88 | CA1 (0.58) | NR4A2KMT2ARXRARXRBRXRG | |
| SCHEMBL7505599 | 0.88 | CA1 (0.58) | NR4A2KMT2ARXRARXRBRXRG | |
| SCHEMBL6228777 | 0.85 | TARBP2 (0.56) | NR4A2KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL23833719 | 0.84 | ALDH1A1 (0.51) | KMT2AADORA3ALDH1A1KDM4EHPGD | |
| SCHEMBL9428384 | 0.84 | NR4A2 (0.69) | NR4A2KMT2ARXRARXRBRXRG | |
| SCHEMBL28462846 | 0.83 | ALDH1A1 (0.52) | KMT2AADORA3ALDH1A1KDM4EHPGD | |
| SCHEMBL8556797 | 0.82 | ALDH1A1 (0.46) | NR4A2KMT2ARXRARXRBRXRG | |
| SCHEMBL8558012 | 0.82 | CA1 (0.44) | NR4A2KMT2ARXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117546851-A | Herbicidal compositions containing uracil compounds of carboxylate fragments and uses thereof | 江苏中旗科技股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| US-8410097-B2 | Heteropyrrole analogs acting on cannabinoid receptors | UNIVERSITY OF CONNECTICUT (US) | 2013-04-02 | — | — | US | disclosed |
| US-8410097-B2 | Heteropyrrole analogs acting on cannabinoid receptors | UNIVERSITY OF CONNECTICUT (US) | 2013-04-02 | — | — | US | disclosed |
| US-8410097-B2 | Heteropyrrole analogs acting on cannabinoid receptors | UNIVERSITY OF CONNECTICUT (US) | 2013-04-02 | — | — | US | disclosed |
| US-20120095047-A1 | Novel Heteropyrrole Analogs Acting on Cannabinoid Receptors | UNIVERSITY OF CONNECTICUT (US) | 2012-04-19 | — | — | US | disclosed |
| US-20120095047-A1 | Novel Heteropyrrole Analogs Acting on Cannabinoid Receptors | UNIVERSITY OF CONNECTICUT (US) | 2012-04-19 | — | — | US | disclosed |
| US-20120095047-A1 | Novel Heteropyrrole Analogs Acting on Cannabinoid Receptors | UNIVERSITY OF CONNECTICUT (US) | 2012-04-19 | — | — | US | disclosed |
| US-8084451-B2 | Heteropyrrole analogs acting on cannabinoid receptors | UNIVERSITY OF CONNECTICUT (US) | 2011-12-27 | — | — | US | disclosed |
| US-8084451-B2 | Heteropyrrole analogs acting on cannabinoid receptors | UNIVERSITY OF CONNECTICUT (US) | 2011-12-27 | — | — | US | disclosed |
| US-8084451-B2 | Heteropyrrole analogs acting on cannabinoid receptors | UNIVERSITY OF CONNECTICUT (US) | 2011-12-27 | — | — | US | disclosed |
| US-20100063050-A1 | NOVEL HETEROPYRROLE ANALOGS ACTING ON CANNABINOID RECEPTORS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2010-03-11 | — | — | US | disclosed |
| US-20100063050-A1 | NOVEL HETEROPYRROLE ANALOGS ACTING ON CANNABINOID RECEPTORS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2010-03-11 | — | — | US | disclosed |
| US-20100063050-A1 | NOVEL HETEROPYRROLE ANALOGS ACTING ON CANNABINOID RECEPTORS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2010-03-11 | — | — | US | disclosed |
| EP-1845972-A2 | NOVEL HETEROPYRROLE ANALOGS ACTING ON CANNABINIOD RECEPTORS | University of Connecticut (US) | 2007-10-24 | — | — | EP | disclosed |
| US-20060189591-A1 | Five-membered heterocyclic derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| WO-2006074445-A2 | NOVEL HETEROPYRROLE ANALOGS ACTING ON CANNABINIOD RECEPTORS | MAKRIYANNIS ALEXANDROS (US) | 2006-07-13 | — | — | WO | disclosed |
| EP-1621537-A1 | FIVE-MEMBERED HETEROCYCLIC DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-02-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189591-A1 | Five-membered heterocyclic derivative | PTGS1, PTGIS, PTGS2 | NR4A2 4500/4885KMT2A 4143/4885RXRA 4633/4885 |
| US-20120095047-A1 | Novel Heteropyrrole Analogs Acting on Cannabinoid Receptors | CNR2, CNR1, GPR18 | NR4A2 627/4885KMT2A 4192/4885RXRA 602/4885 |
| US-20100063050-A1 | NOVEL HETEROPYRROLE ANALOGS ACTING ON CANNABINOID RECEPTORS | CNR2, CNR1, GPR18 | NR4A2 627/4885KMT2A 4192/4885RXRA 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.