SCHEMBL9428396

SCHEMBL9428396

CON1C(C)(C)CC(CCCCNc2nc(Cl)nc(NCCCCCCNc3nc(Cl)nc(NCCCCC4CC(C)(C)N(OC)C(C)(C)C4)n3)n2)CC1(C)C

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.42
LMNA P02545 1/20 0.33
NR1I2 O75469 1/20 0.30
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7458930 0.99 KMT2A (0.40) KMT2ALMNANR1I2AHR
SCHEMBL7976903 0.96 KMT2A (0.37) KMT2ALMNA
SCHEMBL9429384 0.88 KMT2A (0.42) KMT2A
SCHEMBL9427851 0.86 KMT2A (0.40) KMT2A
SCHEMBL9422664 0.86 HTR7 (0.37)
SCHEMBL8651939 0.86
SCHEMBL3141095 0.86 KMT2A (0.45) KMT2ALMNANR1I2AHR
SCHEMBL9428938 0.86 SMN1; SMN2 (0.32) KMT2A
SCHEMBL9429500 0.85 KMT2A (0.49) KMT2ALMNANR1I2AHR
SCHEMBL7456211 0.85 KMT2A (0.49) KMT2ALMNANR1I2AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300544-A Non-migrating 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperdine 1,3,5-triazine derivatives as polymer stabilizers CIBA-GEIGY CORPORATION (US) 1994-04-05 US disclosed
US-5216156-A Stabilizers having functional groups which chemically bond with polymer substrates CIBA-GEIGY CORPORATION (US) 1993-06-01 US disclosed