SCHEMBL7458930

SCHEMBL7458930

CON1C(C)(C)CC(CCCCNc2nc(Cl)nc(NCCCCC3CC(C)(C)N(OC)C(C)(C)C3)n2)CC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.40
LMNA P02545 1/20 0.34
NR1I2 O75469 1/20 0.31
AHR P35869 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9428396 0.99 KMT2A (0.42) KMT2ALMNANR1I2AHR
SCHEMBL7976903 0.97 KMT2A (0.37) KMT2ALMNA
SCHEMBL9422664 0.88 HTR7 (0.37)
SCHEMBL9427851 0.88 KMT2A (0.40) KMT2A
SCHEMBL8651939 0.87
SCHEMBL9429384 0.86 KMT2A (0.42) KMT2A
SCHEMBL714018 0.86 KMT2A (0.43) KMT2ALMNANR1I2AHRCA12
SCHEMBL163157 0.85
SCHEMBL9428938 0.85 SMN1; SMN2 (0.32) KMT2A
SCHEMBL2022080 0.85 KMT2A (0.45) KMT2ALMNANR1I2AHRCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0889085-B1 N,N',N'''-Tris(2,4-bis(1-hydrocarbyloxy-2,2,6,6,-tetramethylpiperidin-4-yl)alkylamino)-s-triazin-6-yl)-3,3'-ethylenediiminodipropylamines, their isomers and bridged derivatives and polymer compositions stabilized therewith CIBA SC HOLDING AG (CH) 2002-07-24 EP disclosed
EP-0889085-A2 N,N',N'''-Tris(2,4-bis(1-hydrocarbyloxy-2,2,6,6,-tetramethylpiperidin-4-yl)alkylamino)-s-triazin-6-yl)-3,3'-ethylenediiminodipropylamines, their isomers and bridged derivatives and polymer compositions stabilized therewith Ciba SC Holding AG (CH) 1999-01-07 EP disclosed
US-5300544-A Non-migrating 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperdine 1,3,5-triazine derivatives as polymer stabilizers CIBA-GEIGY CORPORATION (US) 1994-04-05 US disclosed
US-5216156-A Stabilizers having functional groups which chemically bond with polymer substrates CIBA-GEIGY CORPORATION (US) 1993-06-01 US disclosed