SCHEMBL7976903

SCHEMBL7976903

CON1C(C)(C)CC(CCCCNc2nc(Cl)nc(Cl)n2)CC1(C)C

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.37
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7458930 0.97 KMT2A (0.40) KMT2ALMNA
SCHEMBL9428396 0.96 KMT2A (0.42) KMT2ALMNA
SCHEMBL8651939 0.87
SCHEMBL692772 0.87 KMT2A (0.40) KMT2ALMNA
SCHEMBL698650 0.86 KMT2A (0.40) KMT2ALMNA
SCHEMBL9427851 0.85 KMT2A (0.40) KMT2A
SCHEMBL9422664 0.85 HTR7 (0.37)
SCHEMBL6032704 0.85 KMT2A (0.36) KMT2A
SCHEMBL1892389 0.85 KMT2A (0.44) KMT2ALMNA
SCHEMBL9428938 0.85 SMN1; SMN2 (0.32) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265473-B1 STABILIZER; HEAT AND OXIDATION RESISTANCE; PHOTOSTABILITY CIBA SPECIALTY CHEMICALS CORP. 2001-07-24 US disclosed
WO-1998054174-A1 BLOCK OLIGOMERS CONTAINING 1-HYDROCARBYLOXY-2,2,6,6-TETRAMETHYL-4-PIPERIDYL GROUPS AS STABILIZERS FOR ORGANIC MATERIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-12-03 WO disclosed