SCHEMBL9428567

SCHEMBL9428567

CCCCCCCCON1C(C)(C)CC(Nc2nc(NCCCCCCNc3nc(NC4CC(C)(C)N(OCCCCCCCC)C(C)(C)C4)nc(NC(CCC)C4CC(C)(C)N(OCCCCCCCC)C(C)(C)C4)n3)nc(NC(CCC)C3CC(C)(C)N(OCCCCCCCC)C(C)(C)C3)n2)CC1(C)C

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 4/20 0.34
EHMT1 Q9H9B1 4/20 0.34
FLT3 P36888 1/20 0.33
TYRO3 Q06418 1/20 0.33
MERTK Q12866 1/20 0.33
GAS6 Q14393 1/20 0.33
KCNH3 Q9ULD8 2/20 0.32
KMT2A Q03164 1/20 0.32
DNM2 P50570 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9429013 0.90 KMT2A (0.44) EHMT2EHMT1FLT3TYRO3MERTK
SCHEMBL9428098 0.90 HTR7 (0.33) EHMT2EHMT1KCNH3KMT2ADNM2
SCHEMBL9429497 0.90 KMT2A (0.44) EHMT2EHMT1KCNH3KMT2ADNM2
SCHEMBL7475738 0.89
SCHEMBL9428700 0.87 KMT2A (0.40) KMT2A
SCHEMBL9428379 0.87 KMT2A (0.40) KMT2A
SCHEMBL9428950 0.86 PPARA (0.34) FLT3TYRO3MERTKGAS6KCNH3
SCHEMBL9428066 0.85
SCHEMBL9427762 0.85
SCHEMBL9428294 0.84 FLT3 (0.32) EHMT2EHMT1FLT3TYRO3MERTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300544-A Non-migrating 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperdine 1,3,5-triazine derivatives as polymer stabilizers CIBA-GEIGY CORPORATION (US) 1994-04-05 US disclosed
US-5216156-A Stabilizers having functional groups which chemically bond with polymer substrates CIBA-GEIGY CORPORATION (US) 1993-06-01 US disclosed