Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 3/20 | 0.42 |
| ▸ | MMP3 | P08254 | 3/20 | 0.42 |
| ▸ | MMP7 | P09237 | 3/20 | 0.42 |
| ▸ | MMP9 | P14780 | 3/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805540 | 1.00 | MMP2 (0.50) | MMP2ANPEPMMP1MMP3MMP7 | |
| SCHEMBL15399060 | 0.89 | MMP2 (0.49) | MMP2ANPEPMMP1MMP3MMP7 | |
| SCHEMBL2317032 | 0.89 | MMP2 (0.49) | MMP2ANPEPMMP1MMP3MMP7 | |
| SCHEMBL8830987 | 0.89 | MMP2 (0.49) | MMP2ANPEPMMP1MMP3MMP7 | |
| SCHEMBL7734259 | 0.89 | MMP2 (0.49) | MMP2ANPEPMMP1MMP3MMP7 | |
| SCHEMBL7807884 | 0.86 | MMP2 (0.45) | MMP2ANPEPHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10390625 | 0.85 | POLB (0.51) | MMP2ANPEPMMP1MMP3MMP7 | |
| SCHEMBL7807916 | 0.85 | POLB (0.51) | MMP2ANPEPMMP1MMP3MMP7 | |
| SCHEMBL7811567 | 0.84 | PKM (0.39) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL7020805 | 0.82 | ALDH1A1 (0.48) | MMP2MMP1MMP3MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5317016-A | Pyrrolidylthiocarbapenem derivative | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-05-31 | — | — | US | disclosed |