Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.74 |
| ▸ | PDE10A | Q9Y233 | 13/20 | 0.54 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7195324 | 0.88 | FFAR1 (0.60) | ALOX5PDE10ACYSLTR1HTR2BFFAR1 | |
| SCHEMBL10692490 | 0.86 | ALOX5 (1.00) | ALOX5PDE10ACYSLTR1FFAR1AKR1B1 | |
| SCHEMBL9505352 | 0.85 | ALOX5 (0.85) | ALOX5PDE10ACYSLTR1FFAR1AKR1B1 | |
| SCHEMBL9427517 | 0.84 | ALOX5 (0.50) | ALOX5PDE10A | |
| SCHEMBL10692276 | 0.82 | ALOX5 (1.00) | ALOX5CYSLTR1 | |
| SCHEMBL9428614 | 0.81 | PDE10A (0.52) | ALOX5PDE10AFFAR1ALOX5AP | |
| SCHEMBL7972473 | 0.79 | CYSLTR1 (0.57) | ALOX5CYSLTR1FFAR1AKR1B1 | |
| SCHEMBL6584268 | 0.75 | FFAR1 (0.60) | ALOX5CYSLTR1FFAR1AKR1B1 | |
| SCHEMBL9390096 | 0.74 | ALOX5 (0.57) | ALOX5PDE10ACYSLTR1 | |
| SCHEMBL9390093 | 0.74 | ALOX5 (0.57) | ALOX5PDE10ACYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071988-A | Antiu lcer agents, antiallergens cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-12-10 | — | — | US | claimed |
| US-5364944-A | Antiinflammatory, antiallergic and cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-11-15 | — | — | US | disclosed |
| US-5218124-A | Antiinflammatory agents, antiallergens and cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |
| US-5071988-A | Antiu lcer agents, antiallergens cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |