Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 1.00 |
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.63 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.62 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.61 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505352 | 0.92 | ALOX5 (0.85) | ALOX5CYSLTR1FFAR1AKR1B1GPBAR1 | |
| SCHEMBL10692276 | 0.89 | ALOX5 (1.00) | ALOX5CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9428833 | 0.86 | ALOX5 (0.74) | ALOX5CYSLTR1FFAR1AKR1B1PDE10A | |
| SCHEMBL1419872 | 0.85 | FFAR1 (0.77) | ALOX5CYSLTR1FFAR1AKR1B1GPBAR1 | |
| SCHEMBL1419751 | 0.84 | CYSLTR1 (0.73) | ALOX5CYSLTR1FFAR1AKR1B1GPBAR1 | |
| SCHEMBL8800199 | 0.84 | ALOX5 (0.72) | ALOX5CYSLTR1FFAR1AKR1B1GPBAR1 | |
| SCHEMBL1419915 | 0.84 | ALOX5 (0.72) | ALOX5CYSLTR1FFAR1AKR1B1GPBAR1 | |
| SCHEMBL8902567 | 0.84 | ALOX5 (0.72) | ALOX5CYSLTR1FFAR1AKR1B1GPBAR1 | |
| SCHEMBL13772730 | 0.81 | GPBAR1 (0.70) | ALOX5CYSLTR1FFAR1AKR1B1GPBAR1 | |
| SCHEMBL9058159 | 0.81 | CYSLTR1 (0.71) | ALOX5CYSLTR1FFAR1AKR1B1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | claimed |
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | claimed |
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | disclosed |