Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | SOD1 | P00441 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9428878 | 0.99 | MEN1 (0.53) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL9429593 | 0.89 | SOD1 (0.57) | MEN1KMT2AALDH1A1MAPTHRH1 | |
| SCHEMBL9384076 | 0.84 | POLB (0.57) | MEN1KMT2APOLBALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9384967 | 0.83 | POLB (0.56) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL9429935 | 0.82 | MAPT (0.57) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL9428710 | 0.80 | HRH1 (0.48) | HRH1GAA | |
| Hydrochloric Acid SCHEMBL9428097 | 0.79 | HRH1 (0.47) | MEN1KMT2ASMN1; SMN2HRH1LMNA | |
| SCHEMBL9428246 | 0.79 | MEN1 (0.52) | MEN1KMT2AALDH1A1HRH1 | |
| SCHEMBL15340905 | 0.78 | KMT2A (0.64) | MEN1KMT2APOLBALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9428320 | 0.78 | MEN1 (0.51) | MEN1KMT2AALDH1A1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |