Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 6/20 | 0.56 |
| ▸ | DRD4 | P21917 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 5/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428850 | 0.89 | MEN1 (0.54) | SOD1KMT2AALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL9428878 | 0.88 | MEN1 (0.53) | SOD1DRD4KMT2AALDH1A1MAPT | |
| SCHEMBL9429398 | 0.88 | HTR1A (0.56) | HTR1AKMT2AALDH1A1MAPTHRH1 | |
| Hydrochloric Acid SCHEMBL9428830 | 0.87 | ALDH1A1 (0.56) | HTR1AKMT2AALDH1A1MAPTHRH1 | |
| SCHEMBL9388604 | 0.84 | KMT2A (0.60) | SOD1HTR1AKMT2AALDH1A1MAPT | |
| SCHEMBL9429617 | 0.81 | TSHR (0.62) | HTR1ADRD4KMT2AALDH1A1LMNA | |
| SCHEMBL9428879 | 0.81 | HTR1A (0.49) | HTR1AKMT2AALDH1A1HRH1DRD2 | |
| SCHEMBL9428710 | 0.81 | HRH1 (0.48) | HRH1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL9429271 | 0.81 | TSHR (0.65) | HTR1ADRD4KMT2AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9428097 | 0.80 | HRH1 (0.47) | KMT2ALMNAHRH1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |