Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | FPR2 | P25090 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429270 | 0.86 | TP53 (0.60) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL9384406 | 0.85 | LMNA (0.61) | MAPTLMNAHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL9428850 | 0.82 | MEN1 (0.54) | MAPTLMNAALDH1A1SMN1; SMN2KMT2A | |
| Oxalic Acid SCHEMBL9384506 | 0.82 | LMNA (0.57) | MAPTLMNAHTTALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9428878 | 0.81 | MEN1 (0.53) | MAPTLMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL9429073 | 0.81 | ALOX15 (0.50) | MAPTLMNAHTTTSHRALDH1A1 | |
| SCHEMBL9428792 | 0.80 | ALOX15 (0.51) | LMNATSHRALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9428577 | 0.79 | ALOX15 (0.50) | MAPTLMNATSHRALDH1A1KMT2A | |
| SCHEMBL9429593 | 0.77 | SOD1 (0.57) | MAPTLMNAHTTTSHRALDH1A1 | |
| SCHEMBL9429265 | 0.77 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |