Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.47 |
| ▸ | HRH1 | P35367 | 7/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428719 | 0.90 | HRH3 (0.47) | HRH3HRH1HRH2KDM4E | |
| SCHEMBL9428669 | 0.86 | HRH3 (0.64) | HRH3HRH1HRH2KDM4E | |
| SCHEMBL9385661 | 0.85 | ALDH1A1 (0.48) | HRH3HRH1KDM4E | |
| SCHEMBL9428426 | 0.85 | HRH3 (0.43) | HRH3HRH1HRH2KDM4E | |
| SCHEMBL9429765 | 0.83 | HRH3 (0.52) | HRH3HRH1MAOB | |
| Oxalic Acid SCHEMBL9388811 | 0.83 | KDM4E (0.53) | HRH3HRH1KDM4E | |
| SCHEMBL9429182 | 0.83 | HRH3 (0.64) | HRH3HRH1HRH2KDM4E | |
| SCHEMBL9388387 | 0.82 | HTR1A (0.46) | HRH3HRH1HRH2KDM4E | |
| SCHEMBL9428383 | 0.81 | MAPT (0.59) | HRH1MAOB | |
| Hydrochloric Acid SCHEMBL9385389 | 0.81 | HTR1A (0.46) | HRH3HRH1HRH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |