Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429259 | 1.00 | POLB (0.34) | POLBMAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL10530994 | 0.87 | PDE3A (0.38) | POLBMAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL9770262 | 0.85 | POLB (0.35) | POLBMAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL10403829 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2 | |
| SCHEMBL28435235 | 0.80 | MAPT (0.43) | POLBMAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL28473803 | 0.80 | MAPT (0.43) | POLBMAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL8600205 | 0.79 | POLB (0.40) | POLBMAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL10543158 | 0.79 | POLB (0.40) | POLBMAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL10490784 | 0.78 | MAPT (0.37) | POLBMAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL10401867 | 0.76 | TSHR (0.34) | POLBMAPTPDE3ASLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5275816-A | Cephalosporin derivatives | BEECHAM GROUP P.L.C. (GB) | 1994-01-04 | — | — | US | disclosed |