Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21525764 | 0.72 | PTGS2 (0.41) | KDM4EALDH1A1 | |
| SCHEMBL487560 | 0.69 | ALDH1A1 (0.50) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5355608 | 0.65 | PTGS2 (0.49) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL19374620 | 0.65 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDACHELCK | |
| SCHEMBL9810575 | 0.65 | ALDH1A1 (0.53) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL8541971 | 0.64 | APEX1 (0.75) | APEX1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL7352239 | 0.64 | CA12 (0.55) | TSHR | |
| SCHEMBL15754098 | 0.63 | ACHE (0.44) | APEX1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30100430 | 0.62 | CSNK2A1 (0.59) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL91954 | 0.62 | CSNK2A1 (0.59) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130081999-A1 | Bridged Macrocyclic Module Compositions | WHITEFORD JEFFERY A (US) | 2013-04-04 | — | — | US | disclosed |
| US-8182695-B2 | Bridged macrocyclic module compositions | WHITEFORD JEFFERY A (US) | 2012-05-22 | — | — | US | disclosed |
| US-8110679-B2 | Nanofilm and membrane compositions | COVALENT PARTNERS LLC (US) | 2012-02-07 | — | — | US | disclosed |
| US-7767810-B2 | Macrocyclic modules comprising linked cyclic synthon units for use in the formation of selectively permeable membranes | COVALENT PARTNERS, LLC (US) | 2010-08-03 | — | — | US | disclosed |
| US-20100152438-A1 | AMPHIPHILIC MOLECULAR MODULES AND CONSTRUCTS BASED THEREON | COVALENT PARTNERS LLC | 2010-06-17 | — | — | US | disclosed |
| US-7595368-B2 | Nanofilm compositions with polymeric components | COVALENT PARTNERS, LLC (US) | 2009-09-29 | — | — | US | disclosed |
| US-7563890-B2 | Amphiphilic molecular modules and constructs based thereon | COVALENT PARTNERS, LLC (US) | 2009-07-21 | — | — | US | disclosed |
| US-20090114596-A1 | NANOFILM AND MEMBRANE COMPOSITIONS | COVALENT PARTNERS LLC | 2009-05-07 | — | — | US | disclosed |
| US-20080290034-A1 | Bridged macrocyclic module compositions | COVALENT PARTNERS LLC | 2008-11-27 | — | — | US | disclosed |
| US-7432371-B2 | Nanofilm and membrane compositions | COVALENT PARTNERS, LLC (US) | 2008-10-07 | — | — | US | disclosed |
| US-20060270846-A1 | Amphiphilic molecular modules and constructs based thereon | COVALENT PARTNERS, LLC (US) | 2006-11-30 | — | — | US | disclosed |
| US-20060128680-A1 | Macrocyclic module compositions | KRIESEL JOSH | 2006-06-15 | — | — | US | disclosed |
| EP-1667965-A2 | BRIDGED MACROCYCLIC MODULE COMPOSITIONS | Covalent Partners, LLC (US) | 2006-06-14 | — | — | EP | disclosed |
| US-20060041077-A1 | Nanofilm compositions with polymeric components | COVALENT PARTNERS LLC | 2006-02-23 | — | — | US | disclosed |
| US-20050154199-A1 | Bridged macrocyclic module compositions | COVALENT PARTNERS LLC | 2005-07-14 | — | — | US | disclosed |
| WO-2005030711-A2 | BRIDGED MACROCYCLIC MODULE COMPOSITIONS | COVALENT PARTNERS LLC (US) | 2005-04-07 | — | — | WO | disclosed |
| US-20040260085-A1 | Nanofilm and membrane compositions | COVALENT PARTNERS LLC | 2004-12-23 | — | — | US | disclosed |
| US-20040106741-A1 | Nanofilm compositions with polymeric components | COVALENT PARTNERS LLC | 2004-06-03 | — | — | US | disclosed |
| US-20040034223-A1 | Amphiphilic molecular modules and constructs based thereon | COVALENT PARTNERS, LLC. | 2004-02-19 | — | — | US | disclosed |
| US-20030199688-A1 | Macrocyclic module compositions | COVALENT PARTNERS, LLC | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199688-A1 | Macrocyclic module compositions | CYCS, IMMT, INTS9 | APEX1 1592/4885MEN1 204/4885KMT2A 3497/4885 |
| US-20100152438-A1 | AMPHIPHILIC MOLECULAR MODULES AND CONSTRUCTS BASED THEREON | ANXA6, THEM6, ANXA5 | APEX1 2488/4885MEN1 1323/4885KMT2A 2799/4885 |
| US-20050154199-A1 | Bridged macrocyclic module compositions | SBDS, NCL, INTS6 | APEX1 943/4885MEN1 1223/4885KMT2A 3294/4885 |
| US-20060128680-A1 | Macrocyclic module compositions | CYCS, IMMT, INTS9 | APEX1 1592/4885MEN1 204/4885KMT2A 3497/4885 |
| US-20040034223-A1 | Amphiphilic molecular modules and constructs based thereon | ANXA6, THEM6, ANXA5 | APEX1 2488/4885MEN1 1323/4885KMT2A 2799/4885 |
| US-20040260085-A1 | Nanofilm and membrane compositions | CLPTM1, APMAP, PHOSPHO1 | APEX1 1482/4885MEN1 2215/4885KMT2A 4088/4885 |
| US-20130081999-A1 | Bridged Macrocyclic Module Compositions | SBDS, NCL, INTS6 | APEX1 948/4885MEN1 1259/4885KMT2A 3432/4885 |
| US-20060270846-A1 | Amphiphilic molecular modules and constructs based thereon | ANXA6, THEM6, ANXA5 | APEX1 2488/4885MEN1 1323/4885KMT2A 2799/4885 |
| US-20080290034-A1 | Bridged macrocyclic module compositions | SBDS, NCL, INTS6 | APEX1 943/4885MEN1 1223/4885KMT2A 3294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.