Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.58 |
| ▸ | HRH1 | P35367 | 4/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9429389 | 0.99 | SIGMAR1 (0.56) | SIGMAR1HRH1ADRA1DADRA1AADRA1B | |
| SCHEMBL9428701 | 0.96 | SIGMAR1 (0.58) | SIGMAR1HRH1ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL9429187 | 0.95 | SIGMAR1 (0.57) | SIGMAR1HRH1ADRA1DADRA1AADRA1B | |
| SCHEMBL9429643 | 0.92 | MEN1 (0.55) | SIGMAR1HRH1ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL9428451 | 0.91 | MEN1 (0.54) | SIGMAR1HRH1ADRA1DADRA1AADRA1B | |
| SCHEMBL9429541 | 0.87 | SIGMAR1 (0.52) | SIGMAR1HRH1ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL9428790 | 0.86 | SIGMAR1 (0.51) | SIGMAR1HRH1ADRA1DADRA1AADRA1B | |
| SCHEMBL9428808 | 0.84 | KCNJ1 (0.51) | HRH1ADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL9429273 | 0.84 | HTR1A (0.51) | SIGMAR1HRH1ADRA1DADRA1AADRA1B | |
| SCHEMBL9383628 | 0.83 | KCNJ1 (0.63) | SIGMAR1HRH1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |