Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428251 | 0.90 | DRD2 (0.48) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL9428419 | 0.88 | HRH3 (0.49) | HRH1HRH3 | |
| SCHEMBL9428545 | 0.88 | HTR1A (0.56) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL9429269 | 0.85 | HTR1A (0.49) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL9428781 | 0.83 | HTR1A (0.46) | HTR1ADRD2HTR2ADRD3ALDH1A1 | |
| SCHEMBL9428783 | 0.81 | DRD2 (0.54) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL9428736 | 0.81 | DRD3 (0.53) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL9428435 | 0.78 | DRD2 (0.58) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| SCHEMBL9429332 | 0.77 | DRD2 (0.53) | HTR1ADRD2HTR2ADRD3TMEM97 | |
| Hydrochloric Acid SCHEMBL9428939 | 0.77 | DRD2 (0.56) | HTR1ADRD2HTR2ADRD3TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |