Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.58 |
| ▸ | HTR1A | P08908 | 3/20 | 0.58 |
| ▸ | HTR2A | P28223 | 3/20 | 0.58 |
| ▸ | DRD3 | P35462 | 3/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | HRH1 | P35367 | 2/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9428939 | 0.99 | DRD2 (0.56) | DRD2HTR1AHTR2ADRD3TMEM97 | |
| SCHEMBL9429989 | 0.88 | GPR84 (0.60) | DRD2HTR1AHTR2ADRD3TMEM97 | |
| Hydrochloric Acid SCHEMBL9428431 | 0.87 | GPR84 (0.58) | DRD2HTR1AHTR2ADRD3TMEM97 | |
| SCHEMBL9428990 | 0.84 | CYP1A2 (0.52) | DRD2DRD3GPR84ALDH1A1SMN1; SMN2 | |
| SCHEMBL9428545 | 0.82 | HTR1A (0.56) | DRD2HTR1AHTR2ADRD3TMEM97 | |
| SCHEMBL9429342 | 0.80 | DRD3 (0.56) | DRD2HTR1AHTR2ADRD3TMEM97 | |
| SCHEMBL9429042 | 0.79 | HTR2A (0.42) | DRD2HTR2ADRD3HRH1GPR84 | |
| SCHEMBL9429626 | 0.78 | HTR1A (0.51) | DRD2HTR1AHTR2ADRD3TMEM97 | |
| SCHEMBL7033807 | 0.77 | HTR1A (0.80) | DRD2HTR1AHTR2ADRD3TMEM97 | |
| Oxalic Acid SCHEMBL9428165 | 0.76 | KDM4E (0.57) | DRD2HTR1AHTR2ADRD3TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |