Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429769 | 0.94 | LTB4R2 (0.49) | LTB4R2OXTRAVPR1AFFAR1AKR1B1 | |
| SCHEMBL9429437 | 0.85 | LTB4R2 (0.48) | LTB4R2OXTRAVPR1APTPN1HDAC1 | |
| SCHEMBL9430109 | 0.83 | OXTR (0.42) | LTB4R2OXTRAVPR1AMMEFFAR1 | |
| SCHEMBL9429387 | 0.83 | LTB4R2 (0.46) | LTB4R2OXTRAVPR1AMMEFFAR1 | |
| SCHEMBL9429910 | 0.80 | LTB4R2 (0.53) | LTB4R2OXTRAVPR1AFFAR1AKR1B1 | |
| SCHEMBL9429450 | 0.79 | AGTR1 (0.42) | LTB4R2 | |
| SCHEMBL2225 | 0.79 | LTB4R2 (0.54) | LTB4R2OXTRAVPR1AHDAC1HDAC6 | |
| SCHEMBL1986 | 0.79 | LTB4R2 (0.53) | LTB4R2OXTRAVPR1AHDAC1HDAC6 | |
| SCHEMBL9429460 | 0.77 | LTB4R2 (0.53) | LTB4R2OXTRAVPR1AFFAR1AKR1B1 | |
| SCHEMBL2305 | 0.77 | LTB4R2 (0.50) | LTB4R2OXTRAVPR1AFFAR1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5369110-A | Hypotensive agents, cardiac insufficiency treatment | CIBA-GEIGY CORPORATION (US) | 1994-11-29 | — | — | US | disclosed |
| EP-0490820-A2 | Biphenylyl compounds | CIBA-GEIGY AG (CH) | 1992-06-17 | — | — | EP | disclosed |