Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9580536 | 0.62 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL13071295 | 0.62 | CRHR1 (0.34) | CRHR1KDM4E | |
| SCHEMBL4246772 | 0.60 | POLB (0.34) | CRHR1KDM4E | |
| SCHEMBL16187464 | 0.58 | SIRT2 (0.36) | CRHR1 | |
| SCHEMBL9430117 | 0.58 | — | — | |
| SCHEMBL17843983 | 0.57 | CRHR1 (0.33) | CRHR1KDM4E | |
| SCHEMBL17971688 | 0.56 | KDM4E (0.34) | KDM4E | |
| SCHEMBL17843995 | 0.56 | GAA (0.41) | KDM4E | |
| SCHEMBL317299 | 0.55 | RAPGEF4 (0.50) | KDM4E | |
| SCHEMBL26200975 | 0.55 | GRIN2D (0.39) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338860-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-08-16 | — | — | US | disclosed |
| EP-0547445-A1 | 4-(substituted)amino-3-aryl-pyrrolinone-2 derivatives and their use as herbicides | BAYER AG (DE) | 1993-06-23 | — | — | EP | disclosed |