Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252810 | 0.80 | — | — | |
| SCHEMBL922358 | 0.73 | — | — | |
| SCHEMBL6439988 | 0.72 | ALDH1A1 (0.35) | NPC1RAB9ASMN1; SMN2ADRA2AADRA2B | |
| SCHEMBL4622035 | 0.69 | — | — | |
| SCHEMBL922254 | 0.69 | — | — | |
| SCHEMBL29002822 | 0.69 | KDM4E (0.42) | SMN1; SMN2 | |
| SCHEMBL13221093 | 0.69 | — | — | |
| SCHEMBL389839 | 0.69 | — | — | |
| SCHEMBL9031733 | 0.69 | — | — | |
| SCHEMBL919996 | 0.68 | ADRA2A (0.33) | SMN1; SMN2ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994020489-A1 | THIENYLOXYBUTENYL DERIVATIVE | SANKYO COMPANY, LIMITED (JP) | 1994-09-15 | — | — | WO | disclosed |