Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PPID | Q08752 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1120544 | 0.86 | RAB9A (0.44) | SMN1; SMN2MEN1KMT2ACTDSP1GAA | |
| SCHEMBL1120517 | 0.84 | ALDH1A1 (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1120585 | 0.83 | MAPT (0.43) | SMN1; SMN2MEN1KMT2AGAATSHR | |
| SCHEMBL8624227 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2MEN1KMT2ACTDSP1GAA | |
| SCHEMBL4458579 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2MEN1KMT2ACTDSP1GAA | |
| SCHEMBL27811356 | 0.82 | CYP4F2 (0.41) | SMN1; SMN2MEN1KMT2ACTDSP1LTA4H | |
| SCHEMBL1120579 | 0.82 | NOTUM (0.45) | SMN1; SMN2MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL1120687 | 0.82 | MAPT (0.48) | SMN1; SMN2MEN1KMT2AGAAALDH1A1 | |
| Phenylhydrazine SCHEMBL28002499 | 0.81 | ALDH1A1 (0.40) | SMN1; SMN2MEN1KMT2ACTDSP1GAA | |
| SCHEMBL3662111 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2ACTDSP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374647-A | Anticoagulants, thromboxane synthase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1994-12-20 | — | — | US | disclosed |
| US-5096897-A | Antiallergens, antiischemic agents, treatment of asthma | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |
| US-5039670-A | Anticoagulants, antiasthma, antiallergens | BAYER AKTIENGESELLSCHAFT (DE) | 1991-08-13 | — | — | US | disclosed |
| CN-1051354-A | Replace cycloalkanes also [b] indoline-and-indol-7 sulfonamide | BAYER AG (DE) | 1991-05-15 | — | — | CN | disclosed |