SCHEMBL9430503

SCHEMBL9430503

C=C(C)CNC(=O)/C=C(C)/C=C/[C@@]1(F)C[C@@H]1c1ccc(Br)c(Br)c1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.32
RARB P10826 1/20 0.32
RARG P13631 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9515305 1.00 RXRA (0.32) RXRARARBRARG
SCHEMBL9429915 1.00 RXRA (0.32) RXRARARBRARG
SCHEMBL9430436 1.00 RXRA (0.32) RXRARARBRARG
SCHEMBL9515734 0.87 HRH3 (0.31) RXRARARBRARG
SCHEMBL9515730 0.87 MEN1 (0.34) RXRARARBRARG
SCHEMBL9516900 0.84
SCHEMBL9191175 0.82 KCNJ6 (0.35) RXRARARBRARG
SCHEMBL9194001 0.80 MMP1 (0.36)
SCHEMBL9193857 0.80 HCRTR1 (0.37)
SCHEMBL9136260 0.78 HTT (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5352822-A Insecticides; miticides; nematocides ROUSSEL UCLAF (FR) 1994-10-04 US disclosed
US-5229424-A Insecticides, acaricides THE WELLCOME FOUNDATION LIMITED (GB) 1993-07-20 US disclosed