Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.67 |
| ▸ | HTR1D | P28221 | 10/20 | 0.60 |
| ▸ | HTR1B | P28222 | 10/20 | 0.60 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | MPO | P05164 | 3/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9077110 | 0.80 | HTR1D (0.67) | HTR1AHTR1DHTR1BHTR2AMPO | |
| SCHEMBL8784534 | 0.80 | HTR1A (1.00) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL8506288 | 0.75 | HTR1D (1.00) | HTR1AHTR1DHTR1BHTR2AMPO | |
| SCHEMBL734706 | 0.73 | MPO (0.57) | HTR1AHTR2AMPO | |
| SCHEMBL26508359 | 0.72 | HTR7 (0.71) | HTR1AHTR1DHTR1BHTR2AMPO | |
| SCHEMBL26508398 | 0.72 | MPO (0.94) | HTR1AHTR1DHTR1BHTR2AMPO | |
| SCHEMBL26508337 | 0.72 | MPO (0.67) | HTR1AHTR1DHTR1BHTR2AMPO | |
| SCHEMBL26508379 | 0.72 | HTR1A (0.75) | HTR1AHTR1DHTR1BHTR2AMPO | |
| SCHEMBL26508375 | 0.72 | MPO (0.67) | HTR1AHTR1DHTR1BHTR2AMPO | |
| SCHEMBL26508389 | 0.72 | MPO (0.67) | HTR1AHTR1DHTR1BHTR2AMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994002477-A1 | IMIDAZOLE, TRIAZOLE AND TETRAZOLE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1994-02-03 | — | — | WO | disclosed |