SCHEMBL8440564

SCHEMBL8440564

O=C(O)c1cc2c(I)cccc2s1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 2/20 0.63
F9 P00740 1/20 0.63
F10 P00742 1/20 0.63
SLC9A1 P19634 6/20 0.55
BCL2L1 Q07817 1/20 0.53
PLK4 O00444 2/20 0.45
AURKA O14965 2/20 0.45
DAPK3 O43293 2/20 0.45
CHEK2 O96017 2/20 0.45
CDK1 P06493 2/20 0.45
PIM1 P11309 2/20 0.45
CDK2 P24941 2/20 0.45
MAPK9 P45984 2/20 0.45
CSNK1D P48730 2/20 0.45
GSK3A P49840 2/20 0.45
GSK3B P49841 2/20 0.45
CSNK2A1 P68400 2/20 0.45
DYRK1A Q13627 2/20 0.45
AURKB Q96GD4 2/20 0.45
PLK3 Q9H4B4 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9431027 0.86 PLAU (0.73) PLAUF9F10SLC9A1PLK4
SCHEMBL4853915 0.84 PLAU (0.61) PLAUF9F10SLC9A1DYRK1A
SCHEMBL829725 0.83 SLC9A1 (0.56) PLAUF9F10SLC9A1CSNK1D
SCHEMBL11660706 0.80 BCL2L1 (0.55) SLC9A1BCL2L1PLK4AURKADAPK3
SCHEMBL2893037 0.80 SLC9A1 (0.62) SLC9A1BCL2L1PLK4AURKADAPK3
SCHEMBL1091931 0.79 SLC9A1 (0.63) SLC9A1BCL2L1PLK4AURKADAPK3
SCHEMBL3255241 0.79 BCL2L1 (0.53) PLAUF9F10SLC9A1BCL2L1
SCHEMBL699799 0.79 HDAC3 (0.71) SLC9A1BCL2L1PLK4AURKADAPK3
SCHEMBL29485573 0.79 HDAC3 (0.71) SLC9A1BCL2L1PLK4AURKADAPK3
SCHEMBL29513087 0.79 SLC9A1 (0.63) PLAUSLC9A1BCL2L1PLK4AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-9869027-B2 Cleaning composition and method of manufacturing metal wiring using the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-01-16 US disclosed
US-20160230289-A1 CLEANING COMPOSITION AND METHOD OF MANUFACTURING METAL WIRING USING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2016-08-11 US disclosed
US-9340759-B2 Cleaning composition and method of manufacturing metal wiring using the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-05-17 US disclosed
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20150136728-A1 CLEANING COMPOSITION AND METHOD OF MANUFACTURING METAL WIRING USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-05-21 US disclosed
WO-2014073623-A1 METHOD FOR PROMOTING PLANT GROWTH 住友化学株式会社 (JP) 2014-05-15 WO disclosed
US-5968985-A INHIBITORS OF SODIUM ION/HYDROGEN ION EXCHANGE IN CELLS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-10-19 US disclosed
EP-0773927-A2 BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-05-21 EP disclosed
EP-0769905-A1 FUNGICIDAL COMPOSITIONS CONTAINING 3-PHENYL-PYRAZOLE DERIVATIVES FOR TREATING PROPAGATIVE PLANT STOCK, NOVEL 3-PHENYL-PYRAZOLE DERIVATIVES, AND FUNGICIDAL USES THEREOF RHONE-POULENC AGROCHIMIE (FR) 1997-05-02 EP disclosed
WO-1996004241-A2 BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-02-15 WO disclosed
WO-1996002138-A1 FUNGICIDAL COMPOSITIONS CONTAINING 3-PHENYL-PYRAZOLE DERIVATIVES FOR TREATING PROPAGATIVE PLANT STOCK, NOVEL 3-PHENYL-PYRAZOLE DERIVATIVES, AND FUNGICIDAL USES THEREOF RHONE POULENC AGROCHIMIE (FR) 1996-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH FGF2, BROX, BOLA2; BOLA2B PLAU 4709/4885F9 1446/4885F10 2616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.