Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL944599 | 0.75 | PARP1 (0.31) | PARP1 | |
| SCHEMBL11023512 | 0.72 | MEN1 (0.36) | — | |
| SCHEMBL943496 | 0.72 | XDH (0.30) | — | |
| SCHEMBL14813317 | 0.69 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL153211 | 0.68 | AHR (0.45) | PARP1 | |
| SCHEMBL1057902 | 0.68 | PARP1 (0.52) | PARP1 | |
| SCHEMBL2767946 | 0.66 | PARP1 (0.36) | PARP1 | |
| SCHEMBL24200079 | 0.65 | PARP1 (0.35) | PARP1 | |
| SCHEMBL8118010 | 0.65 | GAA (0.39) | PARP1 | |
| SCHEMBL30768292 | 0.65 | AKT1 (0.40) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629273-B2 | Diazinylpyrazolyl compounds | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-14 | — | — | US | disclosed |
| US-8513260-B2 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2013-08-20 | — | — | US | disclosed |
| EP-2435420-B1 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2013-04-03 | — | — | EP | disclosed |
| US-20120190687-A1 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG | 2012-07-26 | — | — | US | disclosed |
| US-20110124660-A1 | Novel Diazinylpyrazolyl Compounds | BAYER CROPSCIENCE AG (DE) | 2011-05-26 | — | — | US | disclosed |
| US-20110021539-A1 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2011-01-27 | — | — | US | disclosed |
| EP-2266973-A1 | Pyrazinylpyrazole | Bayer CropScience AG (DE) | 2010-12-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021539-A1 | Pyrazinylpyrazoles | CYP4F3, CYP4B1, CYP1A2 | PARP1 3818/4885 |
| US-20120190687-A1 | Pyrazinylpyrazoles | CYP4F3, CYP4B1, CYP1A2 | PARP1 3818/4885 |
| US-20110124660-A1 | Novel Diazinylpyrazolyl Compounds | DDT, PDHX, RECQL | PARP1 1579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.