SCHEMBL1057902

SCHEMBL1057902

Brc1cccc2c1OCC2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.52
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
ADRA1A P35348 1/20 0.36
SLC6A2 P23975 3/20 0.35
SLC6A4 P31645 3/20 0.35
KCNH2 Q12809 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
HTR1A P08908 1/20 0.34
HTR7 P34969 1/20 0.34
HTR2B P41595 1/20 0.34
TMEM97 Q5BJF2 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
HRH1 P35367 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3603870 0.88 PARP1 (0.41) PARP1HTR2AHTR2CADRA2AADRA2B
SCHEMBL4950313 0.86 PARP1 (0.40) PARP1HTR2AHTR2CADRA2AADRA2B
SCHEMBL13738797 0.75 SSTR4 (0.41)
SCHEMBL16127651 0.74 PARP1 (0.52) PARP1HTR2AHTR2CADRA1ASLC6A2
SCHEMBL5542419 0.74 PARP1 (0.56) PARP1HTR2AHTR2CSLC6A2SLC6A4
SCHEMBL293877 0.74 PARP1 (0.52) PARP1HTR2AHTR2CADRA1ASLC6A2
SCHEMBL30363808 0.74 PARP1 (0.52) PARP1HTR2AHTR2CADRA1ASLC6A2
SCHEMBL13651166 0.74 PARP1 (0.52) PARP1HTR2AHTR2CADRA1ASLC6A2
SCHEMBL2007697 0.74 PARP1 (0.52) PARP1HTR2CADRA2AADRA2BADRA2C
SCHEMBL29791283 0.74 PARP1 (0.52) PARP1HTR2AHTR2CADRA2AADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113122061-A Quantum dot ink and preparation method of quantum dot film TCL集团股份有限公司 2021-07-16 CN claimed
EP-4729516-A1 SUBSTITUTED IMIDAZOLE DERIVATIVE, INTERMEDIATE, PREPARATION METHOD THEREFOR AND USE THEREOF Jiangsu NHWA Pharmaceutical Co., Ltd (CN) 2026-04-22 EP disclosed
EP-4698524-A1 TRIARYL AGONISTS OF ALPHA-2 ADRENERGIC RECEPTORS Alceptor Therapeutics, Inc. (US) 2026-02-25 EP disclosed
US-20260042769-A1 TRIARYL AGONISTS OF ALPHA-2 ADRENERGIC RECEPTORS ALCEPTOR THERAPEUTICS INC (US) 2026-02-12 US disclosed
US-20260022096-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS GENECODE (EE) 2026-01-22 US disclosed
EP-4678640-A1 AROMATIC AMIDE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) 2026-01-14 EP disclosed
US-12435060-B2 Acylamino bridged heterocyclic compound, and composition and application thereof BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) 2025-10-07 US disclosed
US-12435054-B2 Therapeutic compounds and methods of use GENENTECH, INC. (US) 2025-10-07 US disclosed
EP-4561994-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS Genecode (EE) 2025-06-04 EP disclosed
WO-2025111414-A1 TRPM3-MODULATING BENZOFURAN DERIVATIVES KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-05-30 WO disclosed
EP-1463501-A1 CIS-IMIDAZOLINES AS MDM2 INHIBITORS F. Hoffmann-La Roche AG (CH) 2004-10-06 EP disclosed
US-20030191118-A1 Inhibitors of alpha4 mediated cell adhesion TANABE SEIYAKU CO., LTD. 2003-10-09 US disclosed
US-6617346-B1 Inhibit the interaction of MDM2 protein with a p53-like peptide and have antiproliferative activity HOFFMANN-LA ROCHE INC. 2003-09-09 US disclosed
WO-2003051360-A1 CIS-IMIDAZOLINES AS MDM2 INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2003-06-26 WO disclosed
US-6521666-B1 Inhibitors of α4 mediated cell adhesion TANABE SEIYAKU CO., LTD. (JP) 2003-02-18 US disclosed
EP-0906912-B1 Indanol derivatives, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2003-01-08 EP disclosed
US-6060487-A Indanol compounds ADIR ET COMPAGNIE (FR) 2000-05-09 US disclosed
US-5958927-A PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS ADIR ET COMPAGNIE (FR) 1999-09-28 US disclosed
CN-1218051-A New 2,3-dioxide, indanol compounds, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 1999-06-02 CN disclosed
EP-0906912-A1 Indanol derivatives, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1999-04-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022096-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS CNR1, CDR2, SMN1; SMN2 PARP1 3692/4885HTR2A 1496/4885HTR2C 656/4885
US-20030191118-A1 Inhibitors of alpha4 mediated cell adhesion ITGB4, ITGA4, VCAM1 PARP1 3281/4885HTR2A 2799/4885HTR2C 2342/4885
US-12435054-B2 Therapeutic compounds and methods of use VHL, NQO1, PCSK9 PARP1 1133/4885HTR2A 3742/4885HTR2C 3397/4885
US-20260042769-A1 TRIARYL AGONISTS OF ALPHA-2 ADRENERGIC RECEPTORS ADRB2, ADRB1, ADRB3 PARP1 3836/4885HTR2A 155/4885HTR2C 72/4885
US-12435060-B2 Acylamino bridged heterocyclic compound, and composition and application thereof RIPK1, RIPK3, RIPK4 PARP1 632/4885HTR2A 4631/4885HTR2C 4580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.