SCHEMBL943162

SCHEMBL943162

O=S(=O)(c1ccccc1)c1ccc(SSc2ccc(S(=O)(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 5/20 0.67
SMN1; SMN2 Q16637 4/20 0.50
MAPT P10636 2/20 0.50
HPGD P15428 2/20 0.50
HSD17B10 Q99714 2/20 0.50
MGLL Q99685 1/20 0.50
ALDH1A1 P00352 3/20 0.46
POLB P06746 1/20 0.46
TSHR P16473 3/20 0.44
PKM P14618 1/20 0.44
KMT2A Q03164 2/20 0.43
HSD11B1 P28845 1/20 0.43
LOX P28300 1/20 0.43
MEN1 O00255 1/20 0.43
HTT P42858 1/20 0.42
CYP3A4 P08684 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5051390 0.84 HTR6 (0.93) HTR6SMN1; SMN2MAPTHSD17B10ALDH1A1
SCHEMBL9625568 0.84 HTR6 (0.64) HTR6SMN1; SMN2MAPTHPGDALDH1A1
SCHEMBL7763086 0.82 HTR6 (0.61) HTR6SMN1; SMN2MAPTHPGDALDH1A1
(Phenylsulfonyl)Benzene SCHEMBL28119187 0.82 HTR6 (1.00) HTR6SMN1; SMN2MAPTHSD17B10ALDH1A1
(Phenylsulfonyl)Benzene SCHEMBL29450723 0.82 HTR6 (1.00) HTR6SMN1; SMN2MAPTHSD17B10ALDH1A1
(Phenylsulfonyl)Benzene SCHEMBL13735236 0.82 HTR6 (1.00) HTR6SMN1; SMN2MAPTHSD17B10ALDH1A1
(Phenylsulfonyl)Benzene SCHEMBL29775288 0.82 HTR6 (1.00) HTR6SMN1; SMN2MAPTHSD17B10ALDH1A1
(Phenylsulfonyl)Benzene SCHEMBL30255 0.82 HTR6 (1.00) HTR6SMN1; SMN2MAPTHSD17B10ALDH1A1
(Phenylsulfonyl)Benzene SCHEMBL29473549 0.82 HTR6 (1.00) HTR6SMN1; SMN2MAPTHSD17B10ALDH1A1
SCHEMBL10608103 0.81 HTR6 (0.59) HTR6SMN1; SMN2HPGDALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987516-B2 Process for producing arylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2015-03-24 US disclosed
EP-2468722-B1 Process for producing arylsulfur halotetrafluorides UBE INDUSTRIES (JP) 2014-10-01 EP disclosed
EP-2468721-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2014-02-26 EP disclosed
EP-2468720-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2013-11-27 EP disclosed
EP-2468719-B1 Process for producing arylsulfur pentafluorides UBE INDUSTRIES (JP) 2013-10-16 EP disclosed
EP-2137144-B1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES UBE INDUSTRIES (JP) 2013-07-31 EP disclosed
US-8399720-B2 Methods for producing fluorinated phenylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2013-03-19 US disclosed
EP-2468719-A1 Process for producing arylsulfur pentafluorides UBE Industries, Ltd. (JP) 2012-06-27 EP disclosed
EP-2468721-A1 Process for producing arylsulfur pentafluorides UBE Industries, Ltd. (JP) 2012-06-27 EP disclosed
EP-2468722-A1 Process for producing arylsulfur halotetrafluorides UBE Industries, Ltd. (JP) 2012-06-27 EP disclosed
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-02-04 US disclosed
EP-2137144-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM&T Research, Inc. (US) 2009-12-30 EP disclosed
US-20090287024-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2009-11-19 US disclosed
US-7592491-B2 Process for producing arylsulfur pentafluorides IM&T RESEARCH, INC. (US) 2009-09-22 US disclosed
WO-2008118787-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM & T RESEARCH, INC. (US) 2008-10-02 WO disclosed
US-20080234520-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES IM&T RESEARCH, INC. (US) 2008-09-25 US disclosed
WO-1993013079-A1 ANTIFOLATE QUINAZOLINES AGOURON PHARMACEUTICALS, INC. (US) 1993-07-08 WO disclosed
EP-0248932-B1 PROCESS FOR PREPARING POLYAMIDES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-01-09 EP disclosed
US-4754016-A Process for preparing polyamide with organic phosphine/organic disulfide mixture condensing agent ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-06-28 US disclosed
EP-0248932-A1 Process for preparing polyamides Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-12-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090287024-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA HTR6 476/4885SMN1; SMN2 2262/4885MAPT 3764/4885
US-20080234520-A1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES PFAS, MPST, ARSA HTR6 476/4885SMN1; SMN2 2262/4885MAPT 3764/4885
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA HTR6 476/4885SMN1; SMN2 2262/4885MAPT 3764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.