SCHEMBL943173

SCHEMBL943173

C1CCN(c2nnn[nH]2)CC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP2C19 P33261 1/20 0.37
BCHE P06276 1/20 0.35
ACHE P22303 1/20 0.35
HPGD P15428 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
USP2 O75604 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
ALDH1A1 P00352 3/20 0.32
GAA P10253 2/20 0.32
HSD17B10 Q99714 2/20 0.32
MAPK1 P28482 2/20 0.32
PIM1 P11309 1/20 0.32
TSHR P16473 2/20 0.32
GFER P55789 2/20 0.32
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
NFKB1 P19838 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10274656 1.00 CYP1A2 (0.37) CYP1A2MEN1KMT2ACYP2C19BCHE
SCHEMBL5394656 1.00 CYP1A2 (0.37) CYP1A2MEN1KMT2ACYP2C19BCHE
SCHEMBL31759376 1.00 CYP1A2 (0.37) CYP1A2MEN1KMT2ACYP2C19BCHE
Hydrochloric Acid SCHEMBL28360015 0.98 CYP1A2 (0.36) CYP1A2MEN1KMT2ACYP2C19BCHE
SCHEMBL628830 0.98 MEN1 (0.34) CYP1A2MEN1KMT2ACYP2C19BCHE
SCHEMBL10493476 0.93
SCHEMBL4174000 0.78 PIM1 (0.39) MEN1KMT2ASMN1; SMN2PIM1NPC1
SCHEMBL31759418 0.78 TRPC3 (0.38) MEN1KMT2AHPGDSMN1; SMN2USP2
SCHEMBL31759472 0.78 TRPC3 (0.38) MEN1KMT2AHPGDSMN1; SMN2USP2
SCHEMBL31759401 0.78 TRPC3 (0.38) MEN1KMT2AHPGDSMN1; SMN2USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1246801-B1 METHODS FOR THE SYNTHESES OF ALFENTANIL, SUFENTANIL AND REMIFENTANIL MALLINCKRODT INC (US) 2006-09-20 EP claimed
US-7074935-B2 Methods for the syntheses of alfentanil, sufentanil and remifentanil MALLINCKRODT INC. (US) 2006-07-11 US claimed
US-20260007684-A1 AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF VENTUS THERAPEUTICS U S INC (US) 2026-01-08 US disclosed
US-20260008768-A1 UREA DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF VENTUS THERAPEUTICS U S INC (US) 2026-01-08 US disclosed
US-20240368131-A1 OXOINDOLINYL AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF VENTUS THERAPEUTICS U S INC (US) 2024-11-07 US disclosed
CN-105829307-B Tetrahydroimidazopyridine derivatives as modulators of TNF activity UCB生物制药私人有限公司 2020-07-24 CN disclosed
EP-3080128-B1 IMIDAZOPYRIDAZINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY UCB Biopharma SRL (BE) 2020-06-24 EP disclosed
EP-3080127-B1 IMIDAZOPYRIMIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY UCB Biopharma SRL (BE) 2020-06-24 EP disclosed
EP-3080123-B1 IMIDAZOPYRIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY UCB Biopharma SRL (BE) 2020-06-17 EP disclosed
EP-3080130-B1 TRIAZOLOPYRIDAZINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY UCB Biopharma SRL (BE) 2020-06-03 EP disclosed
EP-3080129-B1 IMIDAZOTRIAZINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY UCB Biopharma SRL (BE) 2020-06-03 EP disclosed
EP-1717221-A1 PROCESSES FOR PRODUCTION OF ALPHA-AMINOOXYKETONES AND ALPHA-HYDROXYKETONES Japan Science and Technology Agency (JP) 2006-11-02 EP disclosed
WO-2005090294-A2 PROCESS OF MAKING α-AMINOOXYKETONE/α-AMINOOXYALDEHYDE AND α-HYDROXYKETONE/α-HYDROXYALDEHYDE COMPOUNDS AND A PROCESS OF MAKING REACTION PRODUCTS FROM CYCLIC α,ß-UNSATURATED KETONE SUBSTRATES AND NITROSO SUBSTRATES JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2005-09-29 WO disclosed
EP-0960102-A1 AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN Du Pont Pharmaceuticals Company (US) 1999-12-01 EP disclosed
US-5880138-A ANTAGONISTS OF EXCITATORY AMINO ACIDS ELI LILLY AND COMPANY (US) 1999-03-09 US disclosed
WO-1998001428-A1 AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN DU PONT PHARMACEUTICALS COMPANY (US) 1998-01-15 WO disclosed
US-5348960-A Inhibitors of ADP-induced blood platelet aggregation, antithrombogenic BRISTOL-MYERS SQUIBB COMPANY (US) 1994-09-20 US disclosed
EP-0330353-B1 TETRAZOLE EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1993-04-07 EP disclosed
US-4968678-A NERVOUS SYSTEM DISORDERS ELI LILLY AND COMPANY (US) 1990-11-06 US disclosed
EP-0330353-A1 Tetrazole excitatory amino acid receptor antagonists ELI LILLY AND COMPANY (US) 1989-08-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008768-A1 UREA DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF NOD1, NLRP3, NOD2 CYP1A2 2180/4885MEN1 4308/4885KMT2A 4683/4885
US-20240368131-A1 OXOINDOLINYL AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF NLRP3, NLRP1, NOD1 CYP1A2 1574/4885MEN1 4618/4885KMT2A 4759/4885
US-20260007684-A1 AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF NOD1, NLRP3, NOD2 CYP1A2 1650/4885MEN1 4331/4885KMT2A 4575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.