Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 2/20 | 0.39 |
| ▸ | PAM | P19021 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11829100 | 0.87 | NAAA (0.56) | NAAADGKAHTR2CEPHX2PRSS1 | |
| SCHEMBL11829013 | 0.87 | NAAA (0.56) | NAAADGKAHTR2CEPHX2PRSS1 | |
| SCHEMBL11837773 | 0.87 | NAAA (0.56) | NAAADGKAHTR2CEPHX2PRSS1 | |
| SCHEMBL11828068 | 0.87 | NAAA (0.56) | NAAADGKAHTR2CEPHX2PRSS1 | |
| SCHEMBL11829329 | 0.87 | NAAA (0.56) | NAAADGKAHTR2CEPHX2PRSS1 | |
| SCHEMBL11832432 | 0.87 | NAAA (0.56) | NAAADGKAHTR2CEPHX2PRSS1 | |
| SCHEMBL9425559 | 0.87 | DGKA (0.57) | NAAADGKAEPHX2PRSS1PRSS2 | |
| SCHEMBL8084714 | 0.83 | EPHX2 (0.54) | NAAADGKAHTR2CEPHX2PRSS1 | |
| SCHEMBL6477414 | 0.82 | ALDH1A1 (0.44) | — | |
| SCHEMBL31307903 | 0.81 | NAAA (0.56) | NAAADGKAHTR2CEPHX2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358949-A | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| EP-0236140-A2 | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |