Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | MMP9 | P14780 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 12/20 | 0.42 |
| ▸ | CA9 | Q16790 | 12/20 | 0.42 |
| ▸ | CA1 | P00915 | 11/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA3 | P07451 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | CA6 | P23280 | 3/20 | 0.38 |
| ▸ | CA5A | P35218 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11176516 | 1.00 | TSHR (0.62) | TSHRALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL8723938 | 1.00 | TSHR (0.62) | TSHRALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL20495987 | 1.00 | TSHR (0.62) | TSHRALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL1606611 | 1.00 | TSHR (0.62) | TSHRALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL1606138 | 0.98 | TSHR (0.65) | TSHRALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL2241904 | 0.93 | TSHR (0.54) | TSHRALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL6621065 | 0.91 | ALDH1A1 (0.61) | TSHRALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL11250193 | 0.90 | LMNA (0.50) | TSHRALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL11250191 | 0.90 | LMNA (0.50) | TSHRALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL13812658 | 0.89 | ALDH1A1 (0.48) | TSHRALDH1A1LMNAKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354756-A | Inhibiting second messenger pathway | CELL THERAPEUTICS, INC. (US) | 1994-10-11 | — | — | US | disclosed |