Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19399623 | 0.78 | KDM4E (0.42) | KDM4CPARP1HTTKDM4EKMT2A | |
| SCHEMBL6933543 | 0.76 | KDM4C (0.54) | KDM4CPARP1HTTHPGDTNKS2 | |
| SCHEMBL29560266 | 0.76 | PARP1 (0.50) | PARP1KDM4EHPGDTNKS2ADORA3 | |
| SCHEMBL1477487 | 0.76 | PARP1 (0.50) | PARP1KDM4EHPGDTNKS2ADORA3 | |
| SCHEMBL28012240 | 0.75 | TUBB4A (0.71) | KDM4CPARP1KDM4ETUBB4ATUBB | |
| SCHEMBL826249 | 0.72 | TYMS (0.49) | — | |
| SCHEMBL5794718 | 0.70 | PARP1 (0.82) | KDM4CPARP1KDM4EKMT2ATNKS2 | |
| SCHEMBL29431542 | 0.70 | PARP1 (0.82) | KDM4CPARP1KDM4EKMT2ATNKS2 | |
| SCHEMBL6643057 | 0.69 | KDM4C (0.52) | KDM4CPARP1HTTKDM4EHPGD | |
| SCHEMBL9129643 | 0.69 | KDM4C (0.56) | KDM4CPARP1KDM4ETUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5330987-A | Substituted pyridopyrimidinones and related heterocycles as angiotensin II antagonists | MERCK & CO., INC. (US) | 1994-07-19 | — | — | US | disclosed |