Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | SNCA | P37840 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433771 | 1.00 | RAB9A (0.62) | RAB9AMAPTNPC1HTTMAPK1 | |
| SCHEMBL9433401 | 0.86 | MAPT (0.64) | RAB9AMAPTNPC1HTTMAPK1 | |
| SCHEMBL9434245 | 0.86 | MAPT (0.64) | RAB9AMAPTNPC1HTTMAPK1 | |
| SCHEMBL9433499 | 0.82 | ALDH1A1 (0.50) | RAB9AMAPTNPC1HTTMAPK1 | |
| SCHEMBL9433818 | 0.82 | EGFR (0.55) | RAB9AMAPTNPC1HTTMAPK1 | |
| SCHEMBL9434011 | 0.81 | ALDH1A1 (0.49) | RAB9AMAPTNPC1HTTMAPK1 | |
| SCHEMBL9433520 | 0.81 | ALDH1A1 (0.49) | RAB9AMAPTNPC1HTTMAPK1 | |
| SCHEMBL9433916 | 0.80 | ALDH1A1 (0.51) | RAB9AMAPTNPC1MAPK1ALDH1A1 | |
| SCHEMBL9434816 | 0.79 | MAPT (0.52) | RAB9AMAPTNPC1MAPK1SNCA | |
| SCHEMBL9433575 | 0.79 | MAPT (0.52) | RAB9AMAPTNPC1MAPK1SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |