Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GYS1 | P13807 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433405 | 0.86 | PDE4A (0.43) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9433930 | 0.84 | GPBAR1 (0.36) | ALDH1A1CYP1A2CYP3A4CYP2C19SLC22A12 | |
| SCHEMBL9433838 | 0.83 | RPS6KA3 (0.50) | KMT2AMAPTRAB9ASLC22A12 | |
| SCHEMBL9433512 | 0.82 | SLC22A12 (0.41) | ALDH1A1CYP3A4CYP2C19RAB9ASLC22A12 | |
| SCHEMBL9434027 | 0.82 | SLC22A12 (0.40) | ALDH1A1TGM2MAPTPOLBLMNA | |
| SCHEMBL9433530 | 0.82 | RPS6KA3 (0.35) | MAPTSLC22A12 | |
| SCHEMBL9433598 | 0.79 | RORC (0.40) | L3MBTL1ALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL9434303 | 0.79 | SLC22A12 (0.46) | ALDH1A1MAPTSLC22A12CYP11B1CYP11B2 | |
| SCHEMBL9433809 | 0.75 | GPBAR1 (0.36) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9434218 | 0.73 | GSTP1 (0.46) | ALDH1A1MEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |