Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.59 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433746 | 1.00 | GLO1 (0.59) | GLO1FBP1CA1CA2CA4 | |
| SCHEMBL9434279 | 0.87 | GLO1 (0.64) | GLO1FBP1CA1CA2CA4 | |
| SCHEMBL9434284 | 0.87 | GLO1 (0.64) | GLO1FBP1CA1CA2CA4 | |
| SCHEMBL9434520 | 0.84 | GLO1 (0.56) | GLO1FBP1CA1CA2CA4 | |
| SCHEMBL9434523 | 0.84 | GLO1 (0.56) | GLO1FBP1CA1CA2CA4 | |
| SCHEMBL9433401 | 0.82 | MAPT (0.64) | GLO1FBP1CA1CA2CA4 | |
| SCHEMBL9434245 | 0.82 | MAPT (0.64) | GLO1FBP1CA1CA2CA4 | |
| SCHEMBL9434470 | 0.81 | ALDH1A1 (0.59) | GLO1FBP1CA1CA2CA4 | |
| SCHEMBL9433735 | 0.81 | GLO1 (0.59) | GLO1FBP1CA1CA2CA4 | |
| SCHEMBL9433715 | 0.81 | GLO1 (0.59) | GLO1FBP1CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |