Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11335090 | 0.84 | ALDH1A1 (0.41) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL590472 | 0.80 | MAOA (0.61) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL9713754 | 0.80 | MAPT (0.50) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL7281646 | 0.78 | MAOB (0.46) | VCAM1MAPTPOLBCYP2C9HPGD | |
| SCHEMBL1343668 | 0.77 | TSHR (0.60) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL8388465 | 0.77 | PDE7A (0.54) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL8390638 | 0.77 | MAOA (0.46) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL592155 | 0.77 | VCAM1 (0.41) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL17870778 | 0.76 | ALDH1A1 (0.55) | VCAM1MAPTCYP1A2POLBCYP2C9 | |
| SCHEMBL19175487 | 0.76 | DTYMK (0.33) | MAPTTDP1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350748-A | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |