Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 2/20 | 0.68 |
| ▸ | ACLY | P53396 | 1/20 | 0.60 |
| ▸ | IKBKB | O14920 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | OGG1 | O15527 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13969608 | 0.81 | LIMK1 (1.00) | LIMK1ACLYIKBKBKDM4EALDH1A1 | |
| SCHEMBL5809803 | 0.80 | ACLY (0.45) | LIMK1ACLYLMNAMAPK1HSD11B1 | |
| SCHEMBL18088617 | 0.76 | KEAP1 (0.42) | LIMK1ACLYALDH1A1EP300KAT2B | |
| SCHEMBL2702750 | 0.73 | LIMK1 (0.68) | LIMK1ACLYIKBKBKDM4EALDH1A1 | |
| SCHEMBL29483598 | 0.73 | LIMK1 (0.68) | LIMK1ACLYIKBKBKDM4EALDH1A1 | |
| SCHEMBL9433865 | 0.72 | LIMK1 (0.62) | LIMK1ACLYIKBKBKDM4EALDH1A1 | |
| SCHEMBL6609258 | 0.71 | LIMK1 (1.00) | LIMK1IKBKBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL11074064 | 0.71 | LIMK1 (0.68) | LIMK1ACLYIKBKBKDM4EALDH1A1 | |
| SCHEMBL649968 | 0.71 | LIMK1 (0.68) | LIMK1ACLYIKBKBKDM4EALDH1A1 | |
| SCHEMBL29604679 | 0.70 | LIMK1 (0.58) | LIMK1ACLYIKBKBHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004057-A1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | C&C Research Laboratories (KR) | 2016-04-13 | — | — | EP | claimed |
| WO-2014196793-A1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | C&C RESEARCH LABORATORIES (KR) | 2014-12-11 | — | — | WO | claimed |
| EP-3004057-A1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | C&C Research Laboratories (KR) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014196793-A1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | C&C RESEARCH LABORATORIES (KR) | 2014-12-11 | — | — | WO | disclosed |