Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433899 | 1.00 | MAPT (0.61) | MAPTRAB9ANPC1GLO1MEN1 | |
| SCHEMBL2726023 | 0.81 | KIF20A (0.66) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL2726026 | 0.81 | KIF20A (0.66) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL31120388 | 0.80 | MAPT (0.58) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL9433464 | 0.78 | GLO1 (0.61) | MAPTRAB9ANPC1GLO1MEN1 | |
| SCHEMBL9433460 | 0.78 | GLO1 (0.61) | MAPTRAB9ANPC1GLO1MEN1 | |
| SCHEMBL9434300 | 0.77 | GLO1 (0.54) | MAPTRAB9ANPC1GLO1MEN1 | |
| SCHEMBL9434299 | 0.77 | GLO1 (0.54) | MAPTRAB9ANPC1GLO1MEN1 | |
| SCHEMBL9433467 | 0.76 | GLO1 (0.56) | MAPTRAB9ANPC1GLO1MEN1 | |
| SCHEMBL9433473 | 0.76 | GLO1 (0.56) | MAPTRAB9ANPC1GLO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |