Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GUSB | P08236 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433473 | 1.00 | GLO1 (0.56) | GLO1KMT2AMEN1NPC1POLB | |
| SCHEMBL9433899 | 0.76 | MAPT (0.61) | GLO1KMT2AMEN1NPC1POLB | |
| SCHEMBL9433902 | 0.76 | MAPT (0.61) | GLO1KMT2AMEN1NPC1POLB | |
| SCHEMBL9434394 | 0.76 | GLO1 (0.54) | GLO1KMT2AMEN1NPC1FBP1 | |
| SCHEMBL9434400 | 0.76 | GLO1 (0.54) | GLO1KMT2AMEN1NPC1FBP1 | |
| SCHEMBL9434470 | 0.75 | ALDH1A1 (0.59) | GLO1KMT2AMEN1NPC1FBP1 | |
| SCHEMBL9433464 | 0.74 | GLO1 (0.61) | GLO1KMT2AMEN1NPC1POLB | |
| SCHEMBL9433460 | 0.74 | GLO1 (0.61) | GLO1KMT2AMEN1NPC1POLB | |
| SCHEMBL9433701 | 0.73 | GLO1 (0.64) | GLO1KMT2ANPC1POLBFBP1 | |
| SCHEMBL9433707 | 0.73 | GLO1 (0.64) | GLO1KMT2ANPC1POLBFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |