Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.71 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.71 |
| ▸ | DRD3 | P35462 | 10/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.63 |
| ▸ | DRD2 | P14416 | 4/20 | 0.63 |
| ▸ | DRD4 | P21917 | 8/20 | 0.60 |
| ▸ | DRD1 | P21728 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7167638 | 0.89 | ABCG2 (0.76) | ABCG2ABCB1DRD3SIGMAR1DRD2 | |
| SCHEMBL9433141 | 0.85 | ABCB1 (0.69) | ABCG2ABCB1DRD3SIGMAR1DRD2 | |
| SCHEMBL7167644 | 0.84 | ABCG2 (0.59) | ABCG2ABCB1DRD3SIGMAR1DRD2 | |
| SCHEMBL9433423 | 0.83 | SMN1; SMN2 (0.73) | ABCG2ABCB1DRD3DRD2 | |
| Bromide SCHEMBL8790411 | 0.81 | ABCB1 (0.62) | ABCG2ABCB1 | |
| SCHEMBL8789531 | 0.80 | ABCB1 (0.81) | ABCG2ABCB1 | |
| Hydrochloric Acid SCHEMBL10659282 | 0.79 | ABCB1 (0.80) | ABCG2ABCB1 | |
| SCHEMBL14721849 | 0.78 | DRD3 (0.79) | DRD3SIGMAR1DRD2DRD4DRD1 | |
| SCHEMBL10360520 | 0.78 | SIGMAR1 (0.65) | ABCG2ABCB1DRD3SIGMAR1DRD2 | |
| SCHEMBL8789315 | 0.78 | ALDH1A1 (0.77) | ABCG2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294621-A | Thieno tetrahydropyridines useful as class III antiarrhythmic agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |